To investigate the influence of intersection structures on the mechanical properties and failure mechanisms of rock materials, a series of uniaxial compression tests on complete red sandstone specimens and specimens with various hole Notebook shapes (T-shape, cross-shape, and shaft-roadway-shape) were conducted by the Instron 1346 servo-controlled
Porous Nanomaterials Targeting Autophagy in Bone Regeneration
Porous nanomaterials (PNMs) are nanosized materials with specially designed porous structures that have been widely used in the bone tissue engineering field due to the fact of their excellent physical and chemical properties such as high porosity, high specific surface area, and ideal biodegradability.Currently, PNMs are mainly used in the followi
Microbiota-directed biotherapeutics: considerations for quality and functional assessment
ABSTRACTMounting evidence points to causative or correlative roles of gut microbiome in the development of a myriad of diseases ranging from gastrointestinal diseases, metabolic diseases to neurological disorders and cancers.Consequently, efforts have been made to develop and apply therapeutics targeting the human microbiome, in particular Apple th
Spatial genetic patterns in African wild dogs reveal signs of effective dispersal across southern Africa
Across much of Africa, decades of civil war, land reforms, and persecution Methylcobalamin by humans have decimated wildlife populations.African wild dogs (Lycaon pictus) have declined dramatically during the past decades, but have shown recent natural recolonisation of some areas.In Angola, they were rediscovered after almost five decades when no
Predicting Plan Failure by Monitoring Action Sequences and Duration
Anticipating failures in agent plan execution is important to enable an agent to develop strategies to avoid or circumvent such failures, allowing the agent to achieve its goal.Plan recognition can be used to infer which plans are CORNSTARCH being executed from observations of sequences of activities being performed by an agent.In this work, we use